Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.1142 | 0.1142 |
Schistosoma mansoni | transient receptor potential channel | 0.0069 | 0.6021 | 0.4809 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.1906 | 0.5 |
Brugia malayi | Transient-receptor-potential like protein | 0.0039 | 0.2618 | 1 |
Brugia malayi | Inositol-1 | 0.0037 | 0.2334 | 0.8914 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.2334 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0069 | 0.6021 | 0.4809 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.1906 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2618 | 0.2618 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.2334 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0069 | 0.6021 | 0.4809 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.2334 | 0.5 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.2334 | 0.5 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.2334 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.2334 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.2334 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.2334 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0105 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.2334 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.1142 | 0.436 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2227 | 0.2227 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0105 | 1 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.2334 | 0.2334 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.2334 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0069 | 0.6021 | 0.4809 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0102 | 0.9608 | 0.9489 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.2334 | 0.5 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0039 | 0.2618 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.5629 | 0.5629 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0069 | 0.6021 | 0.4809 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0039 | 0.2618 | 0.0371 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0102 | 0.9608 | 0.9489 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 1 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0069 | 0.6021 | 0.4809 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0105 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.