Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Echinococcus granulosus | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Echinococcus granulosus | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Plasmodium falciparum | Appr-1-p processing domain protein | 0.0013 | 0.5 | 0.5 |
Trypanosoma brucei | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Toxoplasma gondii | macro domain-containing protein | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Trypanosoma cruzi | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Trypanosoma cruzi | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Mycobacterium ulcerans | lipoprotein LppD | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible lipoprotein LppD | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Giardia lamblia | Protein LRP16 | 0.0013 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.