Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0143 | 0.2232 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0293 | 0.5733 | 0.5 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0143 | 0.2232 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0363 | 0.0363 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0363 | 0.0363 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0266 | 0.0266 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0059 | 0.0266 | 0.0266 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0363 | 0.0363 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0266 | 0.0266 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.0266 | 0.0266 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0363 | 0.0363 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0266 | 0.0266 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0293 | 0.5733 | 0.5 |
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.0193 | 0.3395 | 0.3395 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0266 | 0.0266 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0266 | 0.0266 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.0266 | 0.0266 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0363 | 0.0363 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.0266 | 0.0266 |
Schistosoma mansoni | sodium-bile acid cotransporter | 0.0283 | 0.5495 | 0.5495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0363 | 0.0363 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0143 | 0.2232 | 0.5 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0363 | 0.0363 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.0476 | 1 | 1 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0476 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0476 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0363 | 0.0363 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.0266 | 0.0266 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Onchocerca volvulus | 0.0476 | 1 | 0.5 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0293 | 0.5733 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.