Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | cyclin B, putative | 0.0047 | 0.0788 | 1 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0351 | 0.991 | 0.9903 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0047 | 0.0788 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0047 | 0.0788 | 1 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0125 | 0.3126 | 0.3012 |
Brugia malayi | P38 map kinase family protein 2 | 0.0351 | 0.991 | 1 |
Echinococcus multilocularis | cyclin B | 0.0047 | 0.0788 | 0.0603 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0125 | 0.3126 | 0.3012 |
Entamoeba histolytica | cyclin, putative | 0.0047 | 0.0788 | 1 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0125 | 0.3126 | 0.3012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0202 | 0.078 |
Schistosoma mansoni | cyclin B | 0.0047 | 0.0788 | 0.0598 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0351 | 0.991 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0047 | 0.0788 | 0.0603 |
Trichomonas vaginalis | cyclin B3, putative | 0.0028 | 0.0202 | 0.078 |
Trichomonas vaginalis | cyclins, putative | 0.0047 | 0.0788 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0047 | 0.0788 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0028 | 0.0202 | 0.078 |
Trichomonas vaginalis | cyclins, putative | 0.0047 | 0.0788 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0028 | 0.0202 | 0.078 |
Trichomonas vaginalis | cyclins, putative | 0.0047 | 0.0788 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0047 | 0.0788 | 1 |
Onchocerca volvulus | 0.0047 | 0.0788 | 0.5 | |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0351 | 0.991 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0028 | 0.0202 | 0.078 |
Trichomonas vaginalis | cyclins, putative | 0.0047 | 0.0788 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0354 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0047 | 0.0788 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0788 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.2924 | 0.2804 |
Toxoplasma gondii | hypothetical protein | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0788 | 0.0603 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0351 | 0.991 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0047 | 0.0788 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0351 | 0.991 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0028 | 0.0202 | 0.078 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0047 | 0.0788 | 0.0603 |
Plasmodium falciparum | cyclin | 0.0028 | 0.0202 | 0.5 |
Schistosoma mansoni | cyclin d | 0.0125 | 0.3126 | 0.2984 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0351 | 0.991 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.3126 | 0.3012 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0351 | 0.991 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0351 | 0.991 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0351 | 0.991 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0351 | 0.991 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0351 | 0.991 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.