Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0293 | 0.2129 | 1 |
Echinococcus multilocularis | aminopeptidase N | 0.0995 | 1 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.019 | 0.0975 | 0.0975 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0293 | 0.2129 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0103 | 0 | 0.5 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0103 | 0 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0995 | 1 | 1 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.019 | 0.0975 | 0.407 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0293 | 0.2129 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.0975 | 0.1102 |
Toxoplasma gondii | aminopeptidase N protein | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0805 | 0.7871 | 0.8898 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.0975 | 0.1102 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0103 | 0 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.019 | 0.0975 | 0.4578 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0293 | 0.2129 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Loa Loa (eye worm) | aminopeptidase N | 0.0293 | 0.2129 | 0.2407 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0293 | 0.2129 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0103 | 0 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0293 | 0.2129 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Loa Loa (eye worm) | hypothetical protein | 0.0892 | 0.8846 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.6717 | 0.7593 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Onchocerca volvulus | 0.0995 | 1 | 1 | |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0293 | 0.2129 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0293 | 0.2129 | 0.2129 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0293 | 0.2129 | 0.889 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0293 | 0.2129 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0317 | 0.2395 | 1 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0293 | 0.2129 | 0.2129 |
Brugia malayi | hypothetical protein | 0.0293 | 0.2129 | 0.2129 |
Onchocerca volvulus | 0.0293 | 0.2129 | 0.2129 | |
Trypanosoma cruzi | aminopeptidase, putative | 0.0293 | 0.2129 | 1 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0293 | 0.2129 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0293 | 0.2129 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0103 | 0 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0103 | 0 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0293 | 0.2129 | 0.2129 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0293 | 0.2129 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.