Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Hemolysis (functional) | = 100 % | Lysis of human erythrocytes at a concentration of 1 mM for 30 minutes at 37 degree C | ChEMBL. | 15027875 |
Hemolysis (functional) | = 100 % | Lysis of human erythrocytes at a concentration of 1 mM for 30 minutes at 37 degree C | ChEMBL. | 15027875 |
IC50 (functional) | = 9.5 uM | In vitro antimalarial activity against D2 strain of Plasmodium falciparum | ChEMBL. | 15027875 |
IC50 (functional) | = 9.5 uM | In vitro antimalarial activity against D2 strain of Plasmodium falciparum | ChEMBL. | 15027875 |
IC50 (functional) | = 125 uM | Growth inhibition of Candida albicans JRW#5 | ChEMBL. | 17079152 |
IC50 (functional) | = 125 uM | Growth inhibition of Candida albicans JRW#5 | ChEMBL. | 17079152 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 | 15027875 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.