Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0073 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.8724 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0093 | 1 | 0.5 |
Schistosoma mansoni | jun-related protein | 0.0076 | 0.1276 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.1276 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0093 | 1 | 0.5 |
Echinococcus granulosus | jun protein | 0.0093 | 1 | 0.5 |
Echinococcus multilocularis | jun protein | 0.0093 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 100 uM | Binding affinity of the compound against Ras SPA enzyme | ChEMBL. | 10794697 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.