Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0868 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0466 | 0.5335 | 0.5335 |
Schistosoma mansoni | voltage-gated potassium channel | 0.001 | 0.0035 | 0.0035 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0868 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.001 | 0.0035 | 0.0035 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0189 | 0.2124 | 0.5 |
Trypanosoma cruzi | putative prolyl carboxypeptidase, putative | 0.0189 | 0.2124 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0189 | 0.2124 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0257 | 0.0257 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.0189 | 0.2124 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0033 | 0.0308 | 0.0308 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0189 | 0.2124 | 0.5 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0189 | 0.2124 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0033 | 0.0308 | 0.0308 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0033 | 0.0308 | 0.0308 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.0189 | 0.2124 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0189 | 0.2124 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.0343 | 0.0343 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0189 | 0.2124 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0033 | 0.0308 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 1 | 1 |
Giardia lamblia | Serine peptidase, putative | 0.0189 | 0.2124 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0189 | 0.2124 | 0.2124 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0189 | 0.2124 | 0.2124 |
Schistosoma mansoni | lysosomal Pro-Xaa carboxypeptidase (S28 family) | 0.0868 | 1 | 1 |
Giardia lamblia | Thymus-specific serine protease precursor | 0.0189 | 0.2124 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel | 0.001 | 0.0035 | 0.0035 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0031 | 0.0283 | 0.1331 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.0189 | 0.2124 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0189 | 0.2124 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2124 | 0.2124 |
Echinococcus granulosus | voltage gated potassium channel | 0.001 | 0.0035 | 0.0035 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0189 | 0.2124 | 0.2124 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.0343 | 0.0343 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.001 | 0.0035 | 0.0035 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Onchocerca volvulus | 0.0189 | 0.2124 | 0.5 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0466 | 0.5335 | 0.5335 |
Schistosoma mansoni | voltage-gated potassium channel | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0189 | 0.2124 | 0.2124 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0035 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0189 | 0.2124 | 0.2124 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0031 | 0.0283 | 0.1331 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0189 | 0.2124 | 1 |
Toxoplasma gondii | serine carboxypeptidase s28 protein | 0.0189 | 0.2124 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.