Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Erv1 / Alr family protein | 0.0068 | 1 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.7556 | 0.7556 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0068 | 1 | 0.5 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0068 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7556 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7556 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.7556 | 0.7556 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.7556 | 0.7556 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.7556 | 0.7556 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0068 | 1 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.7556 | 0.7556 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.7556 | 0.7556 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0068 | 1 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.7556 | 0.7556 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7556 | 1 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0068 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0068 | 1 | 0.5 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0068 | 1 | 0.5 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0068 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7556 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7556 | 1 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0068 | 1 | 0.5 |
Brugia malayi | RNA binding protein | 0.0062 | 0.7556 | 0.7556 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0068 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.