Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | polo-like protein kinase, putative | 0.005 | 0.1821 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0025 | 0.0331 | 0.1819 |
Schistosoma mansoni | alpha-glucosidase | 0.0074 | 0.3251 | 0.3251 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3382 | 0.3382 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0145 | 0.7431 | 0.7431 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0086 | 0.396 | 0.396 |
Echinococcus granulosus | geminin | 0.0189 | 0.9996 | 0.9996 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0189 | 0.9996 | 0.9996 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.005 | 0.1821 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0019 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.005 | 0.1821 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.9996 | 0.9996 |
Schistosoma mansoni | kinase | 0.0025 | 0.037 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1001 | 0.1001 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.9996 | 0.9996 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.1821 | 0.1821 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.005 | 0.1821 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0086 | 0.396 | 0.396 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.005 | 0.1821 | 0.1821 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0189 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2919 | 0.2919 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.005 | 0.1821 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0086 | 0.396 | 0.396 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.005 | 0.1821 | 0.4599 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0025 | 0.0331 | 0.1819 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Giardia lamblia | Kinase, PLK | 0.005 | 0.1821 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0086 | 0.396 | 0.396 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.005 | 0.1821 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1821 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0086 | 0.396 | 1 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0189 | 1 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.005 | 0.1821 | 0.1821 |
Schistosoma mansoni | alpha-glucosidase | 0.0074 | 0.3251 | 0.3251 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.005 | 0.1821 | 0.1821 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.