Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.3498 | 0.3498 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4995 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4995 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.4995 | 0.4995 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0101 | 1 | 0.5 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0101 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.3498 | 0.3498 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4995 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.4995 | 0.4995 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0101 | 1 | 1 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0101 | 1 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0101 | 1 | 0.5 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0101 | 1 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1472 | 0.1472 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.3498 | 0.3498 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4995 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0101 | 1 | 0.5 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.4995 | 0.4995 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0101 | 1 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.4995 | 0.4995 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4995 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0101 | 1 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.4995 | 0.4995 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1472 | 0.1472 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0101 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.4995 | 0.4995 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0101 | 1 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.3498 | 0.3498 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.