Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | hexokinase type 2 | 0.019 | 0.1231 | 0.5 |
Plasmodium falciparum | V-type H(+)-translocating pyrophosphatase, putative | 0.0693 | 1 | 1 |
Treponema pallidum | hexokinase (hxk) | 0.019 | 0.1231 | 0.5 |
Schistosoma mansoni | hexokinase | 0.019 | 0.1231 | 0.5 |
Plasmodium vivax | V-type H(+)-translocating pyrophosphatase, putative | 0.0693 | 1 | 1 |
Plasmodium vivax | vacuolar-type H+ pumping pyrophosphatase, putative | 0.0693 | 1 | 1 |
Trypanosoma cruzi | vacuolar-type proton translocating pyrophosphatase 1 | 0.0693 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.019 | 0.1231 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.019 | 0.1231 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.019 | 0.1231 | 1 |
Trypanosoma cruzi | Vacuolar proton pyrophosphatase 1, putative | 0.0693 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0181 | 0.1468 |
Brugia malayi | Hexokinase family protein | 0.019 | 0.1231 | 1 |
Onchocerca volvulus | 0.019 | 0.1231 | 1 | |
Echinococcus multilocularis | hexokinase | 0.019 | 0.1231 | 0.5 |
Plasmodium falciparum | V-type K+-independent H+-translocating inorganic pyrophosphatase | 0.0693 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.019 | 0.1231 | 1 |
Loa Loa (eye worm) | hexokinase type II | 0.019 | 0.1231 | 1 |
Echinococcus multilocularis | hexokinase | 0.019 | 0.1231 | 0.5 |
Onchocerca volvulus | 0.019 | 0.1231 | 1 | |
Echinococcus granulosus | hexokinase | 0.019 | 0.1231 | 0.5 |
Onchocerca volvulus | 0.019 | 0.1231 | 1 | |
Entamoeba histolytica | hexokinase 2 | 0.019 | 0.1231 | 0.5 |
Brugia malayi | hexokinase | 0.019 | 0.1231 | 1 |
Echinococcus granulosus | hexokinase | 0.019 | 0.1231 | 0.5 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 2, putative | 0.0693 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.019 | 0.1231 | 0.5 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 1 | 0.0693 | 1 | 1 |
Toxoplasma gondii | V-type H(+)-translocating pyrophosphatase VP1 | 0.0693 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.019 | 0.1231 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.