Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0406 | 0.7241 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0385 | 0.6611 | 0.7077 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.0385 | 0.6611 | 0.2784 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.034 | 0.5304 | 0.5392 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.0385 | 0.6611 | 0.2784 |
Loa Loa (eye worm) | glutamate receptor | 0.0406 | 0.7241 | 0.7241 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 0.6611 | 0.6611 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.593 | 0.593 |
Loa Loa (eye worm) | hypothetical protein | 0.05 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0462 | 0.8878 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.05 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 0.6611 | 0.6611 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0368 | 0.6119 | 0.8166 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog | 0.0385 | 0.6611 | 0.897 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.