Detailed information for compound 808159

Basic information

Technical information
  • TDR Targets ID: 808159
  • Name: (5E)-3-(3-chlorophenyl)-5-[(4-iodophenyl)meth ylidene]-2-sulfanylidene-1,3-thiazolidin-4-on e
  • MW: 457.736 | Formula: C16H9ClINOS2
  • H donors: 0 H acceptors: 1 LogP: 5.81 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Ic1ccc(cc1)/C=C\1/SC(=S)N(C1=O)c1cccc(c1)Cl
  • InChi: 1S/C16H9ClINOS2/c17-11-2-1-3-13(9-11)19-15(20)14(22-16(19)21)8-10-4-6-12(18)7-5-10/h1-9H/b14-8+
  • InChiKey: KZSCRJCLLMABQI-RIYZIHGNSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (5E)-3-(3-chlorophenyl)-5-[(4-iodophenyl)methylene]-2-thioxo-thiazolidin-4-one
  • (5E)-3-(3-chlorophenyl)-5-[(4-iodophenyl)methylene]-2-thioxo-4-thiazolidinone
  • (5E)-3-(3-chlorophenyl)-5-(4-iodobenzylidene)-2-thioxo-thiazolidin-4-one
  • BIM-0012880.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0008 0.0075 0.0176
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus granulosus g protein coupled receptor 0.0008 0.0075 0.0196
Schistosoma mansoni opsin-like receptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.0075 0.0196
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.4272 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0075 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0075 0.0196
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0075 0.0176
Schistosoma mansoni opsin-like receptor 0.0008 0.0075 0.0176
Echinococcus granulosus serotonin receptor 0.0008 0.0075 0.0196
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0439 0.1028
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0075 0.0075
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0439 0.1145
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus orexin receptor type 2 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi Serotonin receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni hypothetical protein 0.0008 0.0075 0.0176
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.0075 0.0196
Brugia malayi GnHR receptor homolog 0.0008 0.0075 0.0196
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.0075 0.0196
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.0075 0.0176
Echinococcus granulosus hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0075 0.0176
Schistosoma mansoni hypothetical protein 0.0008 0.0075 0.0176
Echinococcus granulosus g protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0075 0.0196
Schistosoma mansoni myosin xvIII 0.0008 0.0075 0.0176
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0089 1 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus sex peptide receptor 0.0008 0.0075 0.0196
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.3833 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Toxoplasma gondii hypothetical protein 0.0089 1 0.5
Schistosoma mansoni histamine h1 receptor 0.0008 0.0075 0.0176
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni adenoreceptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.3833 1
Schistosoma mansoni amine GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.0075 0.0196
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0011 0.0439 0.0439
Echinococcus multilocularis sex peptide receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.4272 1
Echinococcus granulosus neuropeptide receptor A26 0.0008 0.0075 0.0196
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0075 0.0075
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0089 1 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine receptor 0.0008 0.0075 0.0176
Echinococcus granulosus neuropeptide receptor 0.0008 0.0075 0.0196
Schistosoma mansoni opsin-like receptor 0.0008 0.0075 0.0176
Brugia malayi putative neuropeptide receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0075 0.0176
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.0075 0.0196
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.0075 0.0196
Echinococcus multilocularis orexin receptor type 2 0.0008 0.0075 0.0196
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.0075 0.0075
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis neuropeptide receptor A26 0.0008 0.0075 0.0196
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0008 0.0075 0.5
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.0075 0.0196
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.3833 1
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0439 0.1028
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi RE15519p 0.0008 0.0075 0.0196
Echinococcus granulosus fmrfamide receptor 0.0008 0.0075 0.0196
Echinococcus granulosus allatostatin A receptor 0.0008 0.0075 0.0196
Echinococcus granulosus neuropeptide s receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus somatostatin receptor 0.0008 0.0075 0.0196
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0439 0.1145
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.0075 0.0196
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.0075 0.0196
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0008 0.0075 0.0075
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.0075 0.0196
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.0075 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0075 0.0196
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi sulfakinin receptor protein 0.0008 0.0075 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0075 0.0196
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.0075 0.0196
Onchocerca volvulus Neuropeptide F receptor homolog 0.0008 0.0075 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0075 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Brugia malayi Dopamine receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis allatostatin A receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis neuropeptide s receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0075 0.0196
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni amine GPCR 0.0008 0.0075 0.0176
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.0075 0.0075
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0075 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi Serotonin receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0089 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.0075 0.0196
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0075 0.0176
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0439 0.1145
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.0075 0.0196
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.3833 0.3833
Echinococcus granulosus g protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis G protein coupled receptor 139 0.0008 0.0075 0.0196
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0439 0.1145
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni amine GPCR 0.0008 0.0075 0.0176
Schistosoma mansoni neuropeptide receptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Schistosoma mansoni amine GPCR 0.0008 0.0075 0.0176
Brugia malayi Dopamine receptor protein 1 0.0008 0.0075 0.0196
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0075 0.0196
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine receptor 0.0008 0.0075 0.0176
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis serotonin receptor 0.0008 0.0075 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0075 0.0196
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.0075 0.0196
Schistosoma mansoni biogenic amine receptor 0.0008 0.0075 0.0176
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni amine GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Brugia malayi ORL1-like opioid receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi neuropeptide F receptor 0.0008 0.0075 0.0196
Brugia malayi follicle stimulating hormone receptor 0.0008 0.0075 0.0196
Brugia malayi neuropeptide F receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.0075 0.0075
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0439 0.1145
Onchocerca volvulus 0.0008 0.0075 0.5
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.3518 1
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Brugia malayi AKH receptor 0.0008 0.0075 0.0196
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0034 0.3202 0.3202
Echinococcus multilocularis serotonin receptor 0.0008 0.0075 0.0196
Brugia malayi Melatonin receptor type 1A 0.0008 0.0075 0.0196
Brugia malayi G-protein coupled receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0075 0.0176
Brugia malayi hypothetical protein 0.0008 0.0075 0.0196
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.0075 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.0075 0.0196
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.3518 1
Echinococcus granulosus neuropeptide receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.0075 0.0176
Schistosoma mansoni neuropeptide receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi G-protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.0075 0.0196
Schistosoma mansoni neuropeptide receptor 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus granulosus g-protein coupled receptor 0.0008 0.0075 0.0196
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0075 0.0196
Onchocerca volvulus 0.0008 0.0075 0.5
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.0075 0.0176
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.0075 0.0176
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.0075 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.0075 0.0196
Brugia malayi larval opioid receptor 0.0008 0.0075 0.0196
Brugia malayi G protein-coupled receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0008 0.0075 0.0176
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.0075 0.0176
Echinococcus multilocularis somatostatin receptor 0.0008 0.0075 0.0196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Brugia malayi Dopamine receptor protein 2 0.0008 0.0075 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0075 0.0176
Onchocerca volvulus 0.0008 0.0075 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.0075 0.0176
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.0075 0.0176
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.0075 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0075 0.0196
Schistosoma mansoni neuropeptide receptor 0.0008 0.0075 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0075 0.0075
Onchocerca volvulus 0.0008 0.0075 0.5
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0075 0.0196

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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