Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.2852 | 0.2852 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0042 | 0.2782 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.0042 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 1 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0072 | 1 | 1 |
Onchocerca volvulus | 0.0072 | 1 | 0.5 | |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0042 | 0.2782 | 0.2782 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0072 | 1 | 1 |
Leishmania major | cyclin | 0.0072 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0042 | 0.2782 | 0.2782 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0042 | 0.2782 | 0.2782 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0042 | 0.2782 | 0.2782 |
Trichomonas vaginalis | cyclin B, putative | 0.0072 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 0.2782 | 0.2782 |
Giardia lamblia | Kinase, CMGC CDK | 0.0042 | 0.2782 | 0.2782 |
Echinococcus multilocularis | cyclin B | 0.0072 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0042 | 0.2782 | 0.2782 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0042 | 0.2782 | 0.2782 |
Trypanosoma cruzi | cyclin, putative | 0.0072 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.2676 | 0.2676 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0042 | 0.2782 | 0.2782 |
Trypanosoma cruzi | cyclin, putative | 0.0072 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase | 0.0042 | 0.2782 | 0.2782 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0072 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0072 | 1 | 1 |
Brugia malayi | cell division control protein 2 homolog | 0.0042 | 0.2782 | 0.2782 |
Trichomonas vaginalis | cyclin B, putative | 0.0072 | 1 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0072 | 1 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0042 | 0.2782 | 0.5 |
Trichomonas vaginalis | cyclins, putative | 0.0049 | 0.4577 | 0.4577 |
Trichomonas vaginalis | cyclins, putative | 0.0072 | 1 | 1 |
Schistosoma mansoni | cyclin B | 0.0072 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0042 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0042 | 0.2782 | 0.2782 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0072 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0072 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0072 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0042 | 0.2782 | 0.2782 |
Trypanosoma cruzi | cyclin 6, putative | 0.0072 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0072 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.2782 | 0.2782 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 0.2782 | 0.2782 |
Plasmodium falciparum | protein kinase 5 | 0.0042 | 0.2782 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0072 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0042 | 0.2782 | 0.2782 |
Trichomonas vaginalis | cyclin B, putative | 0.0072 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0042 | 0.2782 | 0.2782 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0042 | 0.2782 | 0.2782 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.2782 | 0.2782 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.