Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.019 | 0.904 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.019 | 0.904 | 1 |
Brugia malayi | serine/threonine kinase 12 | 0.019 | 0.904 | 0.904 |
Loa Loa (eye worm) | AUR protein kinase | 0.019 | 0.904 | 0.904 |
Echinococcus multilocularis | aurora kinase A | 0.019 | 0.904 | 0.904 |
Echinococcus granulosus | aurora kinase A | 0.019 | 0.904 | 0.904 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0192 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.019 | 0.904 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.019 | 0.904 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.019 | 0.904 | 0.904 |
Echinococcus granulosus | homeodomain interacting protein kinase 3 | 0.0192 | 1 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/HIPK protein kinase | 0.0192 | 1 | 1 |
Echinococcus multilocularis | homeodomain interacting protein kinase 3 | 0.0192 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.019 | 0.904 | 0.904 |
Brugia malayi | serine/threonine protein kinase 6 | 0.019 | 0.904 | 0.904 |
Schistosoma mansoni | protein kinase | 0.019 | 0.904 | 0.904 |
Trichomonas vaginalis | AGC family protein kinase | 0.019 | 0.904 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.019 | 0.904 | 0.904 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0192 | 1 | 1 |
Trypanosoma brucei | aurora B kinase | 0.019 | 0.904 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.019 | 0.904 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.019 | 0.904 | 0.904 |
Trypanosoma cruzi | aurora B kinase, putative | 0.019 | 0.904 | 1 |
Toxoplasma gondii | aurora kinase | 0.019 | 0.904 | 1 |
Leishmania major | protein kinase, putative | 0.019 | 0.904 | 1 |
Giardia lamblia | Aurora kinase | 0.019 | 0.904 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.019 | 0.904 | 0.904 |
Loa Loa (eye worm) | AUR protein kinase | 0.019 | 0.904 | 0.904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.