Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0115 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0031 | 0 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0031 | 0 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0115 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0115 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.005 | 0.2274 | 0.2274 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0115 | 1 | 1 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.005 | 0.2274 | 0.2274 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.005 | 0.2274 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0115 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.005 | 0.2274 | 0.2274 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0115 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0115 | 1 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.0115 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0115 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0115 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0115 | 1 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0115 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.005 | 0.2274 | 0.2274 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0115 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0031 | 0 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0115 | 1 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0115 | 1 | 1 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.005 | 0.2274 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0031 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0115 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.