Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | 0.0838 | 0.5822 | 1 | |
Echinococcus granulosus | protein kinase | 0.0838 | 0.5822 | 0.5852 |
Echinococcus granulosus | serine:threonine protein kinase mig 15 | 0.1184 | 0.9949 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0355 | 0.0051 | 0.0088 |
Echinococcus multilocularis | tumor protein p63 | 0.0379 | 0.034 | 0.0584 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0051 | 0.0051 |
Brugia malayi | Protein kinase domain containing protein | 0.0355 | 0.0051 | 0.0051 |
Schistosoma mansoni | protein kinase | 0.0355 | 0.0051 | 0.0051 |
Echinococcus granulosus | tumor protein p63 | 0.0379 | 0.034 | 0.0342 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0355 | 0.0051 | 0.0051 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0355 | 0.0051 | 0.0051 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0355 | 0.0051 | 0.0088 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0355 | 0.0051 | 0.0051 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0355 | 0.0051 | 0.0088 |
Trypanosoma cruzi | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.035 | 0 | 0.5 |
Loa Loa (eye worm) | STE/STE20/MSN protein kinase | 0.0838 | 0.5822 | 0.5852 |
Schistosoma mansoni | protein kinase | 0.0838 | 0.5822 | 0.5822 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0051 | 0.0051 |
Trypanosoma brucei | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.035 | 0 | 0.5 |
Trypanosoma cruzi | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.035 | 0 | 0.5 |
Onchocerca volvulus | 0.035 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1184 | 0.9949 | 1 |
Loa Loa (eye worm) | STE/STE20/KHS protein kinase | 0.0355 | 0.0051 | 0.0051 |
Schistosoma mansoni | protein kinase | 0.1189 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.