Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.029 | 0.0051 | 0.0051 |
Brugia malayi | Protein kinase domain containing protein | 0.029 | 0.0051 | 0.0051 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.029 | 0.0051 | 0.0051 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.029 | 0.0051 | 0.0051 |
Echinococcus granulosus | tumor protein p63 | 0.0393 | 0.1565 | 0.1573 |
Schistosoma mansoni | protein kinase | 0.029 | 0.0051 | 0.0051 |
Echinococcus multilocularis | 0.0685 | 0.5822 | 1 | |
Echinococcus granulosus | protein kinase | 0.0685 | 0.5822 | 0.5852 |
Echinococcus multilocularis | tumor protein p63 | 0.0393 | 0.1565 | 0.2688 |
Echinococcus granulosus | serine:threonine protein kinase mig 15 | 0.0968 | 0.9949 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.029 | 0.0051 | 0.0088 |
Trypanosoma cruzi | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.0286 | 0 | 0.5 |
Trypanosoma brucei | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.0286 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0968 | 0.9949 | 1 |
Onchocerca volvulus | 0.0286 | 0 | 0.5 | |
Schistosoma mansoni | protein kinase | 0.0971 | 1 | 1 |
Loa Loa (eye worm) | STE/STE20/KHS protein kinase | 0.029 | 0.0051 | 0.0051 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.029 | 0.0051 | 0.0088 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.029 | 0.0051 | 0.0088 |
Trypanosoma cruzi | Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative | 0.0286 | 0 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.029 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | STE/STE20/MSN protein kinase | 0.0685 | 0.5822 | 0.5852 |
Schistosoma mansoni | serine/threonine protein kinase | 0.029 | 0.0051 | 0.0051 |
Schistosoma mansoni | protein kinase | 0.0685 | 0.5822 | 0.5822 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.