Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Echinococcus granulosus | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Mycobacterium tuberculosis | Trehalose synthase TreS | 0.0075 | 0 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Schistosoma mansoni | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Mycobacterium ulcerans | trehalose synthase TreS | 0.0075 | 0 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0106 | 0.3396 | 0.3396 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0106 | 0.3396 | 1 |
Mycobacterium tuberculosis | Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas | 0.0075 | 0 | 0.5 |
Echinococcus multilocularis | geminin | 0.0166 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Mycobacterium leprae | Putative uncharacterized protein ML2045 | 0.0075 | 0 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0106 | 0.3396 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0106 | 0.3396 | 0.3396 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0106 | 0.3396 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0106 | 0.3396 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0106 | 0.3396 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.0106 | 0.3396 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0106 | 0.3396 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0106 | 0.3396 | 0.3396 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0106 | 0.3396 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0106 | 0.3396 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.