Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CDC7 protein kinase | 0.0353 | 0.2783 | 0.27 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | SH2 domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Brugia malayi | SRC-1 | 0.0092 | 0.0276 | 0.0304 |
Echinococcus multilocularis | tyrosine kinase | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0485 | 0.4048 | 0.7326 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0078 | 0.0136 | 0.0023 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.0276 | 0.0175 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.1106 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0078 | 0.0136 | 0.0042 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.0276 | 0.0175 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0353 | 0.2783 | 0.2869 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0092 | 0.0276 | 0.0165 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0078 | 0.0136 | 0.0023 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0078 | 0.0136 | 0.0023 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0095 | 0.0304 | 0.0193 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0092 | 0.0276 | 0.0165 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0136 | 0.0042 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | tyrosine kinase | 0.0078 | 0.0136 | 0.0023 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Giardia lamblia | Kinase, CDC7 | 0.0353 | 0.2783 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.0136 | 0.0023 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0078 | 0.0136 | 0.0023 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0078 | 0.0136 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0092 | 0.0276 | 0.0165 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0092 | 0.0276 | 0.0165 |
Onchocerca volvulus | 0.0353 | 0.2783 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0353 | 0.2783 | 0.5 |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.0353 | 0.2783 | 0.27 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | Protein kinase domain containing protein | 0.0353 | 0.2783 | 0.4971 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.1106 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0353 | 0.2783 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0635 | 0.5484 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0078 | 0.0136 | 0.0023 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | SH2 domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0078 | 0.0136 | 0.0023 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | c src tyrosine kinase | 0.0092 | 0.0276 | 0.0165 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.0276 | 0.0175 |
Schistosoma mansoni | tyrosine kinase | 0.1045 | 0.9419 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0092 | 0.0276 | 0.0165 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0078 | 0.0136 | 0.0023 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0485 | 0.4048 | 0.398 |
Schistosoma mansoni | tyrosine kinase | 0.0092 | 0.0276 | 0.0175 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0092 | 0.0276 | 0.0165 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0092 | 0.0276 | 0.0175 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0353 | 0.2783 | 0.5 |
Loa Loa (eye worm) | SRC-1 | 0.0092 | 0.0276 | 0.0165 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Onchocerca volvulus | 0.0353 | 0.2783 | 1 | |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0092 | 0.0276 | 0.0165 |
Loa Loa (eye worm) | TK protein kinase | 0.0078 | 0.0136 | 0.0023 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0136 | 0.0024 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.0136 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0136 | 0.0023 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0092 | 0.0276 | 0.0165 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0078 | 0.0136 | 0.0023 |
Echinococcus granulosus | tyrosine kinase | 0.0078 | 0.0136 | 0.0023 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.0136 | 0.0042 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.0353 | 0.2783 | 0.27 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.3326 | 0.325 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0092 | 0.0276 | 0.0165 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0136 | 0.0024 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.