Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0291 | 1 | 0.5 |
Loa Loa (eye worm) | TTK protein kinase | 0.0291 | 1 | 1 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0291 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 1 | 0.5 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0291 | 1 | 1 |
Giardia lamblia | Kinase, TTK | 0.0291 | 1 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 1 | 0.5 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0291 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.