Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0272 | 0.027 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Brugia malayi | Reduced folate carrier family protein | 0.0272 | 0.027 | 0.5 |
Onchocerca volvulus | 0.0272 | 0.027 | 1 | |
Onchocerca volvulus | 0.0272 | 0.027 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Loa Loa (eye worm) | reduced folate carrier family protein | 0.0272 | 0.027 | 0.5 |
Onchocerca volvulus | 0.021 | 0.011 | 0.4056 | |
Toxoplasma gondii | hypothetical protein | 0.0998 | 0.2135 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0272 | 0.027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | phosphoribosylamine--glycine ligase | 0.095 | 0.2011 | 1 |
Mycobacterium leprae | PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT | 0.095 | 0.2011 | 1 |
Mycobacterium tuberculosis | Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) | 0.021 | 0.011 | 0.5 |
Onchocerca volvulus | 0.0272 | 0.027 | 1 | |
Echinococcus multilocularis | folate receptor beta | 0.4059 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0963 | 0.2046 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Brugia malayi | folate-like transporter 3 | 0.0272 | 0.027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Mycobacterium ulcerans | phosphoribosylamine--glycine ligase | 0.095 | 0.2011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Onchocerca volvulus | Folate transporter 1 homolog | 0.0272 | 0.027 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Onchocerca volvulus | Folate transporter 1 homolog | 0.0272 | 0.027 | 1 |
Onchocerca volvulus | Folate transporter 1 homolog | 0.0272 | 0.027 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0272 | 0.027 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.