Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0107 | 0.1635 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0328 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1797 | 0.2802 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0076 | 0.0454 | 0.0707 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0107 | 0.1635 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0112 | 0.1797 | 0.2802 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0112 | 0.1797 | 0.2802 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0112 | 0.1797 | 0.2802 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.016 | 0.3632 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0265 | 0.764 | 0.5692 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0233 | 0.6416 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0233 | 0.6416 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0107 | 0.1635 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0328 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0094 | 0.1138 | 0.1773 |
Trichomonas vaginalis | glycoside hydrolase, putative | 0.0293 | 0.8686 | 0.7602 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0454 | 0.0707 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0094 | 0.1138 | 0.1773 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.4164 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0107 | 0.1635 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Onchocerca volvulus | 0.0265 | 0.764 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1635 | 0.2548 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0107 | 0.1635 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0328 | 1 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.016 | 0.3632 | 0.5 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.016 | 0.3632 | 0.5 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0107 | 0.1635 | 0.3183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.