Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Fructose-bisphosphate aldolase | 0.034 | 1 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0116 | 0.1797 | 0.2802 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0116 | 0.1797 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1797 | 0.2802 |
Trichomonas vaginalis | glycoside hydrolase, putative | 0.0304 | 0.8686 | 0.7602 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Onchocerca volvulus | 0.0276 | 0.764 | 0.5 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0116 | 0.1797 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0454 | 0.0707 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0166 | 0.3632 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.4164 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.034 | 1 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0079 | 0.0454 | 0.0707 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0242 | 0.6416 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0166 | 0.3632 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0276 | 0.764 | 0.5692 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0242 | 0.6416 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0166 | 0.3632 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.034 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.