TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 521.001 | Formula: C25H26ClFN2O5S
H donors: 0 H acceptors: 3 LogP: 3.9 Rotable bonds: 10
Rule of 5 violations (Lipinski): 2
SMILES: COc1ccc(cc1OCC1CCOC1)CN(S(=O)(=O)c1ccc(c(c1)Cl)F)Cc1cccnc1
InChi: 1S/C25H26ClFN2O5S/c1-32-24-7-4-18(11-25(24)34-17-20-8-10-33-16-20)14-29(15-19-3-2-9-28-13-19)35(30,31)21-5-6-23(27)22(26)12-21/h2-7,9,11-13,20H,8,10,14-17H2,1H3
InChiKey: NBJWQIXNNOMEQF-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	neuropeptide s receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	tm gpcr rhodopsin	0.0074	0.0244	0.0199
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0074	0.0244	0.0111
Brugia malayi	Serotonin receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	amine GPCR	0.0074	0.0244	0.0111
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	neuropeptide F-like receptor	0.0074	0.0244	0.0111
Schistosoma mansoni	adenoreceptor	0.0074	0.0244	0.0111
Trypanosoma cruzi	polo-like protein kinase, putative	0.0168	0.5648	0.5
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0074	0.0244	0.0199
Brugia malayi	Melatonin receptor type 1A	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0074	0.0244	0.0199
Loa Loa (eye worm)	AGC/RSK/RSK protein kinase	0.0116	0.2675	0.4736
Echinococcus multilocularis	g protein coupled receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	fmrfamide receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Echinococcus multilocularis	neuropeptide receptor A26	0.0074	0.0244	0.0199
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0074	0.0244	0.0111
Brugia malayi	serine/threonine-protein kinase plk-2	0.0168	0.5648	1
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0168	0.5648	1
Brugia malayi	neuropeptide F receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0074	0.0244	0.0199
Echinococcus granulosus	neuropeptide FF receptor 2	0.0074	0.0244	0.0199
Echinococcus multilocularis	g protein coupled receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Schistosoma mansoni	neuropeptide receptor	0.0074	0.0244	0.0111
Echinococcus granulosus	neuropeptides capa receptor	0.0074	0.0244	0.0199
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0074	0.0244	0.0199
Trypanosoma cruzi	polo-like protein kinase, putative	0.0168	0.5648	0.5
Brugia malayi	Dopamine receptor protein 1	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	dro:myosuppressin receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0074	0.0244	0.0111
Echinococcus granulosus	tm gpcr rhodopsin	0.0074	0.0244	0.0199
Echinococcus multilocularis	serotonin receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0074	0.0244	0.0432
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0168	0.5648	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	g protein coupled receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	opsin-like receptor	0.0074	0.0244	0.0111
Echinococcus multilocularis	g protein coupled receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	orexin receptor type 2	0.0074	0.0244	0.0199
Echinococcus granulosus	7tm_1 domain containing protein	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	biogenic amine receptor	0.0074	0.0244	0.0111
Schistosoma mansoni	hypothetical protein	0.0074	0.0244	0.0111
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Brugia malayi	G protein-coupled receptor F59B2.13	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Schistosoma mansoni	histamine h1 receptor	0.0074	0.0244	0.0111
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0168	0.5648	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0074	0.0244	0.0111
Schistosoma mansoni	hypothetical protein	0.0074	0.0244	0.0111
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Echinococcus multilocularis	Serine:threonine protein kinase PLK4	0.0132	0.3593	0.6272
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0074	0.0244	0.0432
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Brugia malayi	sulfakinin receptor protein	0.0074	0.0244	0.0199
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0074	0.0244	0.0199
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0074	0.0244	0.0111
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0074	0.0244	0.0199
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	7TM GPCR rhodopsin	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	allatostatin A receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0074	0.0244	0.0111
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Schistosoma mansoni	myosin xvIII	0.0074	0.0244	0.0111
Schistosoma mansoni	amine GPCR	0.0074	0.0244	0.0111
Loa Loa (eye worm)	G-protein coupled receptor	0.0074	0.0244	0.0432
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0074	0.0244	0.0111
Brugia malayi	Dopamine receptor protein 2	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine receptor	0.0074	0.0244	0.0111
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	neuropeptides capa receptor	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Brugia malayi	neuropeptide F receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	amine GPCR	0.0074	0.0244	0.0111
Schistosoma mansoni	opsin-like receptor	0.0074	0.0244	0.0111
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0074	0.0244	0.0111
Brugia malayi	AKH receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	somatostatin receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	serotonin receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	G-protein coupled receptor	0.0074	0.0244	0.0432
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus multilocularis	neuropeptide Y receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine receptor	0.0074	0.0244	0.0111
Brugia malayi	larval opioid receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0074	0.0244	0.0111
Echinococcus granulosus	g protein coupled receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	neuropeptide receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Brugia malayi	Serotonin receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	neuropeptide s receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	serine/threonine protein kinase	0.0168	0.5648	0.5589
Echinococcus granulosus	sex peptide receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0074	0.0244	0.0199
Schistosoma mansoni	neuropeptide receptor	0.0074	0.0244	0.0111
Echinococcus granulosus	neuropeptide receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	neuropeptide receptor A26	0.0074	0.0244	0.0199
Trypanosoma brucei	polo-like protein kinase	0.0168	0.5648	0.5
Brugia malayi	ribosomal protein S6 kinase alpha 3	0.01	0.1738	0.291
Schistosoma mansoni	opsin-like receptor	0.0074	0.0244	0.0111
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0074	0.0244	0.0432
Echinococcus multilocularis	dro:myosuppressin receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0074	0.0244	0.0111
Brugia malayi	G-protein coupled receptor	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Brugia malayi	GnHR receptor homolog	0.0074	0.0244	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Schistosoma mansoni	neuropeptide F-like receptor	0.0074	0.0244	0.0111
Brugia malayi	G protein-coupled receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	ribosomal protein S6 kinase alpha 3	0.0116	0.2675	0.4608
Echinococcus granulosus	somatostatin receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0074	0.0244	0.0199
Echinococcus granulosus	fmrfamide receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0168	0.5648	1
Echinococcus multilocularis	ribosomal protein S6 kinase alpha 3	0.0116	0.2675	0.4608
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0074	0.0244	0.0111
Schistosoma mansoni	neuropeptide receptor	0.0074	0.0244	0.0111
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0168	0.5648	0.5
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0074	0.0244	0.0199
Loa Loa (eye worm)	neuropeptide F receptor	0.0074	0.0244	0.0432
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0074	0.0244	0.0199
Echinococcus granulosus	neuropeptides capa receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	biogenic amine 5HT receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	growth hormone secretagogue receptor	0.0074	0.0244	0.0111
Giardia lamblia	Kinase, PLK	0.0168	0.5648	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0074	0.0244	0.0199
Brugia malayi	RE15519p	0.0074	0.0244	0.0199
Trichomonas vaginalis	CAMK family protein kinase	0.0168	0.5648	0.5
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0074	0.0244	0.0111
Brugia malayi	Dopamine receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	serotonin receptor	0.0074	0.0244	0.0199
Brugia malayi	ORL1-like opioid receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	amine GPCR	0.0074	0.0244	0.0111
Echinococcus granulosus	G protein coupled receptor 139	0.0074	0.0244	0.0199
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0074	0.0244	0.0111
Echinococcus multilocularis	sex peptide receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	g-protein coupled receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	g protein coupled receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	tm gpcr rhodopsin	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0074	0.0244	0.0111
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0074	0.0244	0.0199
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus multilocularis	G protein coupled receptor 139	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Echinococcus multilocularis	neuropeptide Y receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	neuropeptide Y receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	neuropeptide receptor	0.0074	0.0244	0.0111
Brugia malayi	putative neuropeptide receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Brugia malayi	hypothetical protein	0.0074	0.0244	0.0199
Schistosoma mansoni	hypothetical protein	0.0074	0.0244	0.0111
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0168	0.5648	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0074	0.0244	0.0199
Echinococcus granulosus	hypothetical protein	0.0074	0.0244	0.0199
Loa Loa (eye worm)	melatonin receptor type 1A	0.0074	0.0244	0.0432
Echinococcus granulosus	neuropeptide Y receptor	0.0074	0.0244	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0074	0.0244	0.0111
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0074	0.0244	0.0199
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0074	0.0244	0.0199
Echinococcus granulosus	biogenic amine 5HT receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	amine GPCR	0.0074	0.0244	0.0111
Echinococcus multilocularis	g-protein coupled receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0074	0.0244	0.0199
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0074	0.0244	0.0199
Echinococcus granulosus	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0074	0.0244	0.0432
Echinococcus granulosus	allatostatin A receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Schistosoma mansoni	hypothetical protein	0.0074	0.0244	0.0111
Echinococcus multilocularis	neuropeptide receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0074	0.0244	0.0432
Schistosoma mansoni	neuropeptide f receptor 76f	0.0074	0.0244	0.0111
Brugia malayi	G-protein coupled receptor	0.0074	0.0244	0.0199
Brugia malayi	follicle stimulating hormone receptor	0.0074	0.0244	0.0199
Brugia malayi	putative neuropeptide receptor NPR1	0.0074	0.0244	0.0199
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0074	0.0244	0.0199
Echinococcus multilocularis	fmrfamide receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0074	0.0244	0.0111
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0074	0.0244	0.0199
Echinococcus multilocularis	orexin receptor type 2	0.0074	0.0244	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0074	0.0244	0.0111
Echinococcus granulosus	neuropeptide receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0072	0.0134	0.0238
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0074	0.0244	0.0199
Loa Loa (eye worm)	neuropeptide F receptor	0.0074	0.0244	0.0432
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0074	0.0244	0.0199
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0074	0.0244	0.0199
Schistosoma mansoni	serine/threonine protein kinase	0.0116	0.2675	0.2575
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0074	0.0244	0.0199
Loa Loa (eye worm)	TYRA-2 protein	0.0074	0.0244	0.0432
Echinococcus granulosus	Serine:threonine protein kinase PLK4	0.0132	0.3593	0.6272
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0074	0.0244	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0244	0.0432

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 820859