Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0173 | 0.3092 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0058 | 0.0217 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0448 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0058 | 0.0217 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0058 | 0.0217 | 0.0217 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0448 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0058 | 0.0217 | 0.0703 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0058 | 0.0217 | 0.0534 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0058 | 0.0217 | 0.0217 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0058 | 0.0217 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0058 | 0.0217 | 0.0703 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0173 | 0.3092 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0173 | 0.3092 | 0.3092 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0058 | 0.0217 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0173 | 0.3092 | 0.3092 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0173 | 0.3092 | 0.5 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0212 | 0.4073 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0448 | 1 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0058 | 0.0217 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0173 | 0.3092 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.