Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0166 | 0 | 0.5 | |
Trypanosoma cruzi | diacylglycerol acyltransferase, putative | 0.0166 | 0 | 0.5 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.1162 | 1 | 1 |
Toxoplasma gondii | dgat2l1-prov protein | 0.0166 | 0 | 0.5 |
Leishmania major | diacylglycerol acyltransferase, putative | 0.0166 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1162 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0827 | 0.6638 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0469 | 0.3043 | 0.3043 |
Trypanosoma brucei | diacylglycerol acyltransferase, putative | 0.0166 | 0 | 0.5 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0166 | 0 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0827 | 0.6638 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1162 | 1 | 1 |
Trypanosoma cruzi | diacylglycerol acyltransferase, putative | 0.0166 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.