Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0694 | 1 | 1 |
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.0481 | 0.4874 | 0.4874 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0669 | 0.9392 | 0.9392 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0694 | 1 | 1 |
Echinococcus multilocularis | gamma secretase subunit aph 1 | 0.0481 | 0.4874 | 0.4874 |
Onchocerca volvulus | 0.0694 | 1 | 1 | |
Onchocerca volvulus | Matrilysin homolog | 0.0408 | 0.3117 | 0.3117 |
Loa Loa (eye worm) | hypothetical protein | 0.0694 | 1 | 1 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0408 | 0.3117 | 0.3117 |
Onchocerca volvulus | Deterin homolog | 0.0694 | 1 | 1 |
Brugia malayi | gamma-secretase subunit aph-1 | 0.0481 | 0.4874 | 0.4874 |
Schistosoma mansoni | hypothetical protein | 0.0694 | 1 | 1 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0694 | 1 | 1 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0694 | 1 | 1 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0694 | 1 | 1 |
Echinococcus granulosus | gamma secretase subunit aph 1 | 0.0481 | 0.4874 | 0.4874 |
Loa Loa (eye worm) | hypothetical protein | 0.0694 | 1 | 1 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0694 | 1 | 1 |
Brugia malayi | Matrixin family protein | 0.0445 | 0.4002 | 0.4002 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0694 | 1 | 1 |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.0481 | 0.4874 | 0.4874 |
Loa Loa (eye worm) | matrixin family protein | 0.0408 | 0.3117 | 0.3117 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0669 | 0.9392 | 0.9392 |
Loa Loa (eye worm) | matrixin family protein | 0.0445 | 0.4002 | 0.4002 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.