Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.02 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.02 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | nuclear receptor RXR | 0.0106 | 0.0333 | 0.0333 |
Schistosoma mansoni | thyroid hormone receptor | 0.02 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.02 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.02 | 1 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.02 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.02 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.02 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.02 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.02 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0103 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.02 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.02 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.02 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.02 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.02 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.02 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | steroid hormone receptor | 0.02 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.02 | 1 | 1 |
Onchocerca volvulus | 0.02 | 1 | 0.5 | |
Brugia malayi | nuclear hormone receptor | 0.02 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | nuclear receptor NHR-88 | 0.02 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0103 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.02 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.02 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.02 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.02 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.02 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.02 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.02 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.02 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.02 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.02 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.02 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.02 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0106 | 0.0333 | 0.0333 |
Onchocerca volvulus | Bile acid receptor homolog | 0.02 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.02 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.02 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0333 | 0.0333 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.02 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.02 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.02 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.02 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.02 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.02 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.02 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.02 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0103 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0106 | 0.0333 | 0.0333 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.02 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.