Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutamate receptor NMDA | 0.0071 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0026 | 0.2156 | 0.2156 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0071 | 1 | 1 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0026 | 0.2156 | 0.2156 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.002 | 0.1067 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0026 | 0.2156 | 0.2156 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0022 | 0.1518 | 0.1518 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0026 | 0.2156 | 0.2156 |
Echinococcus granulosus | glutamate receptor 2 | 0.0071 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0071 | 1 | 1 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.0026 | 0.2156 | 0.2156 |
Brugia malayi | FAD binding domain containing protein | 0.0022 | 0.1518 | 0.1518 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0071 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0071 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0071 | 1 | 1 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0022 | 0.1518 | 0.1518 |
Schistosoma mansoni | glutamate receptor kainate | 0.0071 | 1 | 1 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0071 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.002 | 0.1067 | 0.5 |
Trypanosoma cruzi | p450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0022 | 0.1518 | 0.5 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0026 | 0.2156 | 0.2156 |
Brugia malayi | flavodoxin family protein | 0.0022 | 0.1518 | 0.1518 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0071 | 1 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0022 | 0.1518 | 0.1518 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0044 | 0.5392 | 0.5392 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0071 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0071 | 1 | 1 |
Echinococcus multilocularis | NMDA receptor | 0.0026 | 0.2156 | 0.2156 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0071 | 1 | 1 |
Leishmania major | p450 reductase, putative | 0.0022 | 0.1518 | 1 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0071 | 1 | 1 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0022 | 0.1518 | 1 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0022 | 0.1518 | 1 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0022 | 0.1518 | 0.1518 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0071 | 1 | 1 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0022 | 0.1518 | 0.1518 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0026 | 0.2156 | 0.2156 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0071 | 1 | 1 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0022 | 0.1518 | 1 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0026 | 0.2156 | 0.2156 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0071 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0071 | 1 | 1 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0022 | 0.1518 | 0.5 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0071 | 1 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0022 | 0.1518 | 0.5 |
Chlamydia trachomatis | sulfite reductase | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.1518 | 0.1518 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0071 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0022 | 0.1518 | 0.1518 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.2156 | 0.2156 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0071 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0071 | 1 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0044 | 0.5392 | 0.5392 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0026 | 0.2156 | 0.2156 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0022 | 0.1518 | 0.5 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0022 | 0.1518 | 0.5 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.0026 | 0.2156 | 0.2156 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.