Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | geminin | 0.0148 | 0.8275 | 0.8275 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0173 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.2517 | 0.2517 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase 7 | 0.0133 | 0.7275 | 0.7275 |
Leishmania major | histone deacetylase, putative | 0.0173 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0133 | 0.7275 | 0.7275 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0069 | 0.2848 | 0.2848 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0133 | 0.7275 | 0.619 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0069 | 0.2848 | 0.2848 |
Schistosoma mansoni | histone deacetylase | 0.0173 | 1 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0075 | 0.3259 | 0.3259 |
Loa Loa (eye worm) | histone deacetylase | 0.0133 | 0.7275 | 0.7275 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0173 | 1 | 1 |
Giardia lamblia | Histone deacetylase | 0.0173 | 1 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0173 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0069 | 0.2848 | 0.2848 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0133 | 0.7275 | 0.7275 |
Schistosoma mansoni | histone deacetylase | 0.0173 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0133 | 0.7275 | 0.619 |
Trypanosoma brucei | histone deacetylase 3 | 0.0133 | 0.7275 | 0.619 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0173 | 1 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.0133 | 0.7275 | 0.619 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0133 | 0.7275 | 0.619 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2848 | 0.2848 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0173 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0173 | 1 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.014 | 0.776 | 0.776 |
Echinococcus multilocularis | geminin | 0.0148 | 0.8275 | 0.8275 |
Plasmodium vivax | histone deacetylase, putative | 0.0133 | 0.7275 | 0.619 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0075 | 0.3259 | 0.3259 |
Trypanosoma brucei | histone deacetylase 1 | 0.0173 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0047 | 0.1348 | 0.1348 |
Echinococcus multilocularis | histone deacetylase 6 | 0.014 | 0.776 | 0.776 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0133 | 0.7275 | 0.619 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0133 | 0.7275 | 0.7275 |
Echinococcus granulosus | histone deacetylase 1 | 0.0173 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0075 | 0.3259 | 0.3259 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0173 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0133 | 0.7275 | 0.619 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0069 | 0.2848 | 0.2848 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0032 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0173 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0069 | 0.2848 | 0.2848 |
Echinococcus granulosus | jumonji domain containing protein | 0.0032 | 0.0286 | 0.0286 |
Brugia malayi | Histone deacetylase family protein | 0.0133 | 0.7275 | 0.7275 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0133 | 0.7275 | 0.7275 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0133 | 0.7275 | 0.7275 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0173 | 1 | 0.5 |
Trypanosoma brucei | histone deacetylase 4 | 0.0133 | 0.7275 | 0.619 |
Echinococcus granulosus | histone deacetylase 6 | 0.014 | 0.776 | 0.776 |
Entamoeba histolytica | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0173 | 1 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0069 | 0.2848 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0148 | 0.8275 | 0.8275 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0133 | 0.7275 | 0.7275 |
Echinococcus granulosus | histone deacetylase 6 | 0.0133 | 0.7275 | 0.7275 |
Echinococcus granulosus | histone deacetylase 3 | 0.0173 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0173 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0173 | 1 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.2196 | 0.2196 |
Schistosoma mansoni | hypothetical protein | 0.0148 | 0.8275 | 0.8275 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0133 | 0.7275 | 0.7275 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0173 | 1 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0173 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0133 | 0.7275 | 0.7275 |
Echinococcus multilocularis | histone deacetylase | 0.0133 | 0.7275 | 0.7275 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0795 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3002 | 0.3002 |
Brugia malayi | histone deacetylase 11 | 0.0069 | 0.2848 | 0.2848 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0173 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Plasmodium falciparum | histone deacetylase 1 | 0.0173 | 1 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0133 | 0.7275 | 0.7275 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0173 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.