Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0136 | 1 | 1 |
Leishmania major | CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) | 0.0136 | 1 | 0.5 |
Plasmodium vivax | protease, putative | 0.0028 | 0 | 0.5 |
Brugia malayi | Trypsin family protein | 0.007 | 0.3879 | 0.3327 |
Plasmodium falciparum | protease, putative | 0.0028 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.905 | 0.8448 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | CAAX prenyl protease 2 | 0.0136 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0.3879 | 1 | |
Mycobacterium ulcerans | integral membrane protein | 0.0028 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable integral membrane protein | 0.0028 | 0 | 0.5 |
Trichomonas vaginalis | Clan U, family U48, CaaX prenyl peptidase 2-like | 0.0136 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0028 | 0 | 0.5 |
Toxoplasma gondii | CAAX amino terminal protease family protein | 0.0028 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0028 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0 | 0.5 |
Treponema pallidum | hypothetical protein | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | CAAX prenyl protease 2 | 0.0136 | 1 | 1 |
Trypanosoma cruzi | peptidase with unknown catalytic mechanism (family U48) | 0.0136 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0 | 0.5 |
Chlamydia trachomatis | hypothetical protein | 0.0028 | 0 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0136 | 1 | 0.5 |
Entamoeba histolytica | CAAX prenyl protease family | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3879 | 0.3327 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.905 | 0.8448 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3879 | 0.3327 |
Trypanosoma cruzi | CAAX prenyl protease 2, putative | 0.0136 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 1 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0136 | 1 | 1 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0136 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.