Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable integral membrane protein | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | integral membrane protein | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.0089 | 0.3879 | 1 | |
Toxoplasma gondii | hypothetical protein | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | CAAX prenyl protease 2 | 0.0173 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.905 | 0.8448 |
Leishmania major | CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) | 0.0173 | 1 | 0.5 |
Plasmodium vivax | protease, putative | 0.0036 | 0 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0089 | 0.3879 | 0.3327 |
Plasmodium falciparum | protease, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0173 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 1 | 1 |
Trypanosoma cruzi | CAAX prenyl protease 2, putative | 0.0173 | 1 | 0.5 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0173 | 1 | 1 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0173 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.3879 | 0.3327 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.3879 | 0.3327 |
Entamoeba histolytica | CAAX prenyl protease family | 0.0173 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.905 | 0.8448 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0173 | 1 | 0.5 |
Chlamydia trachomatis | hypothetical protein | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | peptidase with unknown catalytic mechanism (family U48) | 0.0173 | 1 | 0.5 |
Toxoplasma gondii | CAAX amino terminal protease family protein | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0036 | 0 | 0.5 |
Treponema pallidum | hypothetical protein | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | CAAX prenyl protease 2 | 0.0173 | 1 | 1 |
Trichomonas vaginalis | Clan U, family U48, CaaX prenyl peptidase 2-like | 0.0173 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0036 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.