Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.3471 | 0.8078 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0126 | 0.3325 | 0.7738 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.3471 | 0.8078 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0445 | 0.1036 |
Brugia malayi | RNA recognition motif domain containing protein | 0.013 | 0.3471 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.2448 | 0.7053 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0152 | 0.4297 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.013 | 0.3471 | 0.8078 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0445 | 0.1282 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0306 | 1 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0306 | 1 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.013 | 0.3471 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.013 | 0.3471 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.3471 | 0.8078 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.2448 | 0.7053 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.2448 | 0.662 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0126 | 0.3325 | 0.958 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0306 | 1 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0445 | 0.1036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0445 | 0.1036 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0306 | 1 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Brugia malayi | RNA binding protein | 0.013 | 0.3471 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.3471 | 0.8078 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0445 | 0.1036 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.013 | 0.3471 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1253 | 0.2669 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.2448 | 0.662 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.4297 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0445 | 0.1282 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0445 | 0.1282 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.4297 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0306 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.3325 | 0.7738 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0445 | 0.1036 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.1253 | 0.3609 |
Brugia malayi | TAR-binding protein | 0.013 | 0.3471 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.013 | 0.3471 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.3471 | 0.8078 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.1253 | 0.2915 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.