Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.004 | 0.5809 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.2103 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0292 | 0.139 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.5809 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.2103 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.5809 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.2103 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2103 | 0.1865 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.2103 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.2103 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.5809 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.2103 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.5809 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0292 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.2103 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.5809 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2103 | 0.1865 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.2103 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.2103 | 1 |
Onchocerca volvulus | 0.0026 | 0.2103 | 0.5 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.2103 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5235 | 0.3967 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2103 | 0.1865 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.5809 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.2103 | 0.5 |
Brugia malayi | hypothetical protein | 0.004 | 0.5809 | 0.4693 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.2103 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.2103 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0292 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0292 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5235 | 0.5092 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.2103 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.5809 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.2103 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.