Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin b | 0.0618 | 1 | 1 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0226 | 0.1875 | 0.1875 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0135 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0135 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0135 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0135 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0618 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0135 | 0 | 0.5 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0226 | 0.1875 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0226 | 0.1875 | 0.1875 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0135 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0226 | 0.1875 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0226 | 0.1875 | 1 |
Toxoplasma gondii | cathepsin B | 0.0226 | 0.1875 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0135 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0618 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0618 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0618 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0618 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0226 | 0.1875 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0226 | 0.1875 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0135 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0135 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0135 | 0 | 0.5 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0135 | 0 | 0.5 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Loa Loa (eye worm) | cathepsin B | 0.0226 | 0.1875 | 0.1875 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0618 | 1 | 1 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0618 | 1 | 1 |
Onchocerca volvulus | 0.0135 | 0 | 0.5 | |
Giardia lamblia | Cathepsin B precursor | 0.0226 | 0.1875 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0618 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0135 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.