Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.089 | 1 | 1 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.089 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0165 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.089 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.032 | 0.2134 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.032 | 0.2134 | 0.2134 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Giardia lamblia | Cathepsin B precursor | 0.032 | 0.2134 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.089 | 1 | 1 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0165 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0165 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.032 | 0.2134 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.089 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.089 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.089 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.089 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.032 | 0.2134 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0165 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.032 | 0.2134 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.032 | 0.2134 | 0.2134 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.032 | 0.2134 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.032 | 0.2134 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0165 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0165 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.089 | 1 | 1 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Echinococcus multilocularis | cathepsin b | 0.089 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0165 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0165 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0165 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0165 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.032 | 0.2134 | 0.2134 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.