Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | pol-related | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0554 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0554 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0554 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Mycobacterium leprae | Isocitrate lyase | 0.026 | 0.4348 | 0.4348 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0554 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0554 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.