Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Mycobacterium leprae | Isocitrate lyase | 0.0257 | 0.4348 | 0.4348 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0549 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0549 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | pol-related | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0549 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0549 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0549 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.