Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | expressed conserved protein | 0.005 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 1 | 1 |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0014 | 0 | 0.5 |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0014 | 0 | 0.5 |
Echinococcus multilocularis | expressed conserved protein | 0.005 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Onchocerca volvulus | Putative nachr subunit | 0.0014 | 0 | 0.5 |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0014 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.005 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0014 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.