Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0347 | 0 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.042 | 0.3624 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.3624 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.042 | 0.3624 | 1 |
Trypanosoma cruzi | cyclic nucleotide phosphodiesterase | 0.0548 | 1 | 0.5 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.042 | 0.3624 | 0.5 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.042 | 0.3624 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.042 | 0.3624 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.042 | 0.3624 | 0.5 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0548 | 1 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.042 | 0.3624 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.