Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0105 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0046 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0105 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.9455 | 0.8155 |
Echinococcus granulosus | glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0046 | 0 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0105 | 1 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0105 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0102 | 0.9455 | 0.9455 |
Schistosoma mansoni | glycogen phosphorylase | 0.0105 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0105 | 1 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0105 | 1 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0105 | 1 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0105 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0105 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0105 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.9455 | 0.8155 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0102 | 0.9455 | 0.9455 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.