Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 0.1063 | 1 |
Onchocerca volvulus | 0.0189 | 1 | 0.5 | |
Onchocerca volvulus | 0.0189 | 1 | 0.5 | |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0189 | 1 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.0189 | 1 | 1 |
Onchocerca volvulus | 0.0189 | 1 | 0.5 | |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0189 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0189 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 0.1063 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0094 | 0.1063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1063 | 0.1063 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0189 | 1 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0094 | 0.1063 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.0189 | 1 | 1 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0189 | 1 | 1 |
Onchocerca volvulus | 0.0189 | 1 | 0.5 | |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0094 | 0.1063 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0189 | 1 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0094 | 0.1063 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0189 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0189 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.