Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | histone deacetylase 1 (HD1) | 0.2796 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2796 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.2218 | 0.7857 | 0.7857 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.026 | 0.026 |
Plasmodium vivax | histone deacetylase, putative | 0.2218 | 0.7857 | 0.5847 |
Echinococcus granulosus | histone deacetylase 6 | 0.2282 | 0.8096 | 0.8096 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.2218 | 0.7857 | 0.7857 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0209 | 0.0406 | 0.0406 |
Echinococcus granulosus | histone deacetylase 7 | 0.2218 | 0.7857 | 0.7857 |
Echinococcus granulosus | histone deacetylase 1 | 0.2796 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.2796 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.2218 | 0.7857 | 0.7857 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2796 | 1 | 0.5 |
Plasmodium vivax | histone deacetylase 2, putative | 0.2218 | 0.7857 | 0.5847 |
Loa Loa (eye worm) | hypothetical protein | 0.2796 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.2796 | 1 | 1 |
Echinococcus granulosus | histone deacetylase | 0.2218 | 0.7857 | 0.7857 |
Brugia malayi | Histone deacetylase 1 | 0.2796 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.2796 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.1235 | 0.4213 | 0.4213 |
Giardia lamblia | Histone deacetylase | 0.2796 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.2218 | 0.7857 | 0.6297 |
Schistosoma mansoni | histone deacetylase | 0.2796 | 1 | 1 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0209 | 0.0406 | 0.0406 |
Plasmodium falciparum | histone deacetylase 1 | 0.2796 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.1404 | 0.4841 | 0.4841 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0555 | 0.1691 | 0.1691 |
Echinococcus multilocularis | histone deacetylase 6 | 0.2218 | 0.7857 | 0.7857 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0108 | 0.0034 | 0.0034 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.2796 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.2218 | 0.7857 | 0.7857 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2796 | 1 | 0.5 |
Entamoeba histolytica | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.2218 | 0.7857 | 0.6297 |
Loa Loa (eye worm) | histone deacetylase | 0.2218 | 0.7857 | 0.7857 |
Echinococcus multilocularis | histone deacetylase 8 | 0.1235 | 0.4213 | 0.4213 |
Trypanosoma brucei | histone deacetylase 4 | 0.2218 | 0.7857 | 0.6297 |
Loa Loa (eye worm) | matrixin family protein | 0.0162 | 0.0234 | 0.0234 |
Echinococcus multilocularis | histone deacetylase 6 | 0.2218 | 0.7857 | 0.7857 |
Echinococcus granulosus | histone deacetylase 6 | 0.2218 | 0.7857 | 0.7857 |
Brugia malayi | Matrixin family protein | 0.0162 | 0.0234 | 0.0234 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2796 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.2282 | 0.8096 | 0.8096 |
Brugia malayi | histone deacetylase 11 | 0.1404 | 0.4841 | 0.4841 |
Schistosoma mansoni | histone deacetylase hda2 | 0.2282 | 0.8096 | 0.8096 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0034 | 0.0034 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0555 | 0.1691 | 0.1691 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.2796 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.2796 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.2796 | 1 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.1235 | 0.4213 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.2218 | 0.7857 | 0.7857 |
Brugia malayi | Histone deacetylase family protein | 0.2218 | 0.7857 | 0.7857 |
Schistosoma mansoni | histone deacetylase hda2 | 0.1235 | 0.4213 | 0.4213 |
Echinococcus granulosus | histone deacetylase 8 | 0.1235 | 0.4213 | 0.4213 |
Echinococcus granulosus | histone deacetylase 3 | 0.2796 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.2218 | 0.7857 | 0.6297 |
Echinococcus multilocularis | histone deacetylase 3 | 0.2796 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.1404 | 0.4841 | 0.1084 |
Trypanosoma brucei | histone deacetylase, putative | 0.2218 | 0.7857 | 0.6297 |
Trypanosoma brucei | histone deacetylase 1 | 0.2796 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2796 | 1 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.2796 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1047 | 0.3515 | 0.3515 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.2218 | 0.7857 | 0.7857 |
Trypanosoma cruzi | histone deacetylase, putative | 0.2218 | 0.7857 | 0.6297 |
Loa Loa (eye worm) | hypothetical protein | 0.1235 | 0.4213 | 0.4213 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Trypanosoma brucei | histone deacetylase 3 | 0.2218 | 0.7857 | 0.6297 |
Brugia malayi | Histone deacetylase family protein | 0.2218 | 0.7857 | 0.7857 |
Leishmania major | histone deacetylase, putative | 0.2796 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0983 | 0.3276 | 0.3276 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2796 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.