Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | casein kinase I gamma | 0.0061 | 0.0578 | 0.0573 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0946 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0057 | 0.0539 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0032 | 0.0268 | 0.0263 |
Brugia malayi | serine/threonine kinase 12 | 0.0057 | 0.0539 | 0.0534 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0036 | 0.0317 | 0.0312 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0057 | 0.0539 | 0.5 |
Echinococcus granulosus | tyrosine kinase | 0.0033 | 0.0279 | 0.0274 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0029 | 0.024 | 0.0235 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0057 | 0.0539 | 1 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0057 | 0.0539 | 0.0534 |
Trichomonas vaginalis | AGC family protein kinase | 0.0057 | 0.0539 | 0.5 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0008 | 0.0016 | 0.0011 |
Brugia malayi | SRC-1 | 0.0036 | 0.0317 | 0.0312 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0057 | 0.0539 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0032 | 0.0268 | 0.0263 |
Entamoeba histolytica | protein kinase, putative | 0.0029 | 0.024 | 0.4442 |
Echinococcus multilocularis | casein kinase I gamma | 0.0061 | 0.0578 | 0.0573 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Loa Loa (eye worm) | TK protein kinase | 0.0029 | 0.024 | 0.0235 |
Schistosoma mansoni | tyrosine kinase | 0.0036 | 0.0317 | 0.0312 |
Brugia malayi | protein-tyrosine kinase | 0.0033 | 0.0279 | 0.0274 |
Entamoeba histolytica | protein kinase , putative | 0.0057 | 0.0539 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0036 | 0.0317 | 0.0312 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0057 | 0.0539 | 1 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0036 | 0.0317 | 0.0312 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0008 | 0.0016 | 0.0011 |
Entamoeba histolytica | protein kinase, putative | 0.0057 | 0.0539 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Schistosoma mansoni | protein kinase | 0.0057 | 0.0539 | 0.0534 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0036 | 0.0317 | 0.0312 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0033 | 0.0279 | 0.0274 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0036 | 0.0317 | 0.0312 |
Echinococcus multilocularis | aurora kinase A | 0.0057 | 0.0539 | 0.0534 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.004 | 0.035 | 0.0345 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0008 | 0.0016 | 0.0011 |
Schistosoma mansoni | tyrosine kinase | 0.0008 | 0.0016 | 0.0011 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0057 | 0.0539 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0061 | 0.0578 | 0.0573 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0036 | 0.0317 | 0.0312 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0008 | 0.0016 | 0.0011 |
Loa Loa (eye worm) | casein kinase | 0.0058 | 0.0545 | 0.054 |
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.0946 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0057 | 0.0539 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Loa Loa (eye worm) | AUR protein kinase | 0.0057 | 0.0539 | 0.0534 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0057 | 0.0539 | 0.0534 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0057 | 0.0539 | 0.0534 |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.0946 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0036 | 0.0317 | 0.0312 |
Giardia lamblia | Aurora kinase | 0.0057 | 0.0539 | 0.5 |
Toxoplasma gondii | aurora kinase | 0.0057 | 0.0539 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0057 | 0.0539 | 0.0534 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0029 | 0.024 | 0.0235 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0036 | 0.0317 | 0.0312 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0033 | 0.0279 | 0.0274 |
Leishmania major | protein kinase, putative | 0.0057 | 0.0539 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0057 | 0.0539 | 0.5 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0008 | 0.0016 | 0.0011 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0036 | 0.0317 | 0.0312 |
Onchocerca volvulus | 0.0007 | 0 | 0.5 | |
Loa Loa (eye worm) | AUR protein kinase | 0.0057 | 0.0539 | 0.0534 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0033 | 0.0279 | 0.0274 |
Trypanosoma brucei | aurora B kinase | 0.0057 | 0.0539 | 0.5 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0057 | 0.0539 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0061 | 0.0578 | 0.0573 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0057 | 0.0539 | 0.5 |
Loa Loa (eye worm) | protein kinase domain-containing protein | 0.0061 | 0.0578 | 0.0573 |
Schistosoma mansoni | tyrosine kinase | 0.0008 | 0.0016 | 0.0011 |
Schistosoma mansoni | tyrosine kinase | 0.0036 | 0.0317 | 0.0312 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0033 | 0.0279 | 0.0274 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0008 | 0.0016 | 0.0011 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0036 | 0.0317 | 0.0312 |
Loa Loa (eye worm) | TK protein kinase | 0.0033 | 0.0279 | 0.0274 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0036 | 0.0317 | 0.0312 |
Echinococcus granulosus | c src tyrosine kinase | 0.0008 | 0.0016 | 0.0011 |
Loa Loa (eye worm) | SRC-1 | 0.0036 | 0.0317 | 0.0312 |
Entamoeba histolytica | protein kinase, putative | 0.0057 | 0.0539 | 1 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0057 | 0.0539 | 0.0534 |
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.0946 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0033 | 0.0279 | 0.0274 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0057 | 0.0539 | 0.0534 |
Echinococcus granulosus | aurora kinase A | 0.0057 | 0.0539 | 0.0534 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.