Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.044 | 0.5011 | 0.5 |
Brugia malayi | heat shock protein 90 | 0.044 | 0.5011 | 0.5 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.035 | 0.252 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.044 | 0.5011 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.044 | 0.5011 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.035 | 0.252 | 0.503 |
Echinococcus multilocularis | heat shock protein | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.035 | 0.252 | 0.4732 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.035 | 0.252 | 0.503 |
Schistosoma mansoni | heat shock protein | 0.044 | 0.5011 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Plasmodium vivax | endoplasmin, putative | 0.044 | 0.5011 | 0.5 |
Schistosoma mansoni | heat shock protein | 0.044 | 0.5011 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.035 | 0.252 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Mycobacterium ulcerans | arylamine N-acetyltransferase Nat | 0.0619 | 1 | 1 |
Treponema pallidum | heat shock protein 90 | 0.035 | 0.252 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Schistosoma mansoni | endoplasmin | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.044 | 0.5011 | 0.5 |
Brugia malayi | Endoplasmin precursor | 0.044 | 0.5011 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.044 | 0.5011 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.044 | 0.5011 | 0.5 |
Plasmodium vivax | heat shock protein 86, putative | 0.044 | 0.5011 | 0.5 |
Loa Loa (eye worm) | endoplasmin | 0.044 | 0.5011 | 0.5 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.044 | 0.5011 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.044 | 0.5011 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.035 | 0.252 | 0.4732 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.044 | 0.5011 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Entamoeba histolytica | heat shock protein 90, putative | 0.044 | 0.5011 | 0.5 |
Schistosoma mansoni | endoplasmin | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Echinococcus granulosus | heat shock protein | 0.044 | 0.5011 | 1 |
Leishmania major | heat shock protein 83-1 | 0.044 | 0.5011 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.044 | 0.5011 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Plasmodium falciparum | heat shock protein 90 | 0.044 | 0.5011 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.044 | 0.5011 | 0.5 |
Entamoeba histolytica | heat shock protein 90, putative | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | heat shock protein, putative | 0.044 | 0.5011 | 0.5 |
Trypanosoma brucei | heat shock protein 90, putative | 0.044 | 0.5011 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.035 | 0.252 | 0.4732 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.