Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | enteropeptidase | 0.0131 | 0.3209 | 0.2151 |
Echinococcus granulosus | laminin | 0.0205 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0116 | 0.1843 | 0.5 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0205 | 1 | 1 |
Echinococcus multilocularis | laminin | 0.0205 | 1 | 1 |
Echinococcus granulosus | Mastin | 0.0131 | 0.3209 | 0.2151 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 1 | 1 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0116 | 0.1843 | 0.0573 |
Brugia malayi | Kringle domain containing protein | 0.0116 | 0.1843 | 0.0573 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0111 | 0.1347 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 1 | 1 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0116 | 0.1843 | 0.0573 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0205 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0121 | 0.2284 | 0.0541 |
Echinococcus multilocularis | fibrillin 1 | 0.0205 | 1 | 1 |
Echinococcus granulosus | Tolloid protein 1 | 0.0205 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0116 | 0.1843 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0116 | 0.1843 | 0.1843 |
Schistosoma mansoni | egf-like domain protein | 0.0205 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0131 | 0.3209 | 0.1674 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0205 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0116 | 0.1843 | 0.0573 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1843 | 0.1843 |
Brugia malayi | Fibulin-1 precursor | 0.0205 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0104 | 0.0676 | 0.5 |
Echinococcus multilocularis | enteropeptidase | 0.0131 | 0.3209 | 0.2151 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0131 | 0.3209 | 0.2151 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0131 | 0.3209 | 0.2151 |
Onchocerca volvulus | Arrow homolog | 0.0205 | 1 | 1 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0116 | 0.1843 | 0.5 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0116 | 0.1843 | 0.5 |
Echinococcus multilocularis | Mastin | 0.0131 | 0.3209 | 0.2151 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0205 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 1 | 1 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0205 | 1 | 1 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0205 | 1 | 1 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0205 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0121 | 0.2284 | 0.0541 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0104 | 0.0676 | 0.5 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0205 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.