Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1275 | 0.1275 |
Onchocerca volvulus | 0.0055 | 0 | 0.5 | |
Onchocerca volvulus | 0.0055 | 0 | 0.5 | |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0055 | 0 | 0.5 |
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.094 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1275 | 0.1275 |
Echinococcus granulosus | geminin | 0.0168 | 0.1275 | 0.1275 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1275 | 0.1275 |
Onchocerca volvulus | 0.0055 | 0 | 0.5 | |
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.094 | 1 | 1 |
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0 | 0.5 |
Onchocerca volvulus | Putative organic anion transporter | 0.0055 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.094 | 1 | 1 |
Onchocerca volvulus | 0.0055 | 0 | 0.5 | |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.094 | 1 | 1 |
Trypanosoma cruzi | MFS transporter, putative | 0.0055 | 0 | 0.5 |
Onchocerca volvulus | 0.0055 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.