Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0628 | 0.7039 | 1 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0359 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0658 | 0.782 | 0.8325 |
Trichomonas vaginalis | Sialidase-1 precursor, putative | 0.0628 | 0.7039 | 1 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0359 | 0 | 0.5 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0359 | 0 | 0.5 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0359 | 0 | 0.5 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0359 | 0 | 0.5 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0742 | 1 | 1 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0359 | 0 | 0.5 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0359 | 0 | 0.5 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0359 | 0 | 0.5 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0359 | 0 | 0.5 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0742 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0718 | 0.9393 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.